N-Acetyl Semax 25MG

N-Acetyl Semax 25MG

$86.00

N-Acetyl Semax is valued for its neuroprotective properties, improving memory and cognitive function. It’s studied for potential benefits in optic nerve diseases and stroke recovery.

83 in stock

Quantity Discount / Amount Price
3 2% $84.28
5 5% $81.70
10 8% $79.12
Summary
N-Acetyl Semax 25MG$86.00
$86.00

Product Usage: This product is designated as a "Novelty Peptide" and is intended solely for specialized applications in controlled settings. It is not intended for any specific biological, therapeutic, or diagnostic use. All information provided on this website is for informational and educational purposes only and should not be construed as guidance for any particular application or usage.

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N-Acetyl Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment, specifically designed to enhance cognitive function and provide neuroprotection. This acetylated variant of Semax is engineered to improve stability and penetration into the brain, making it a promising candidate for cognitive enhancement and neuroprotective applications. The acetylation of the N-terminus increases the peptide's resistance to enzymatic degradation, enhancing its stability and bioavailability. This structural modification allows N-Acetyl Semax to effectively cross the blood-brain barrier and exert its effects on the central nervous system.

Sequence:Ac-Met-Glu-His-Phe-Pro-Gly-Pro2

Molecular Formula: C37H51N9O10S

Molecular Weight:813.92

CAS Number:Not available

  1. Cognitive Enhancement: Research on Semax, the parent compound, has shown significant nootropic effects. A study demonstrated that Semax improved memory and attention in fatigued individuals, achieving a 71% accuracy rate on memory tests compared to 41% in the control group. N-Acetyl Semax is believed to offer similar or enhanced cognitive benefits due to its improved bioavailability.
  2. Neuroprotection: Semax has been shown to upregulate brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), which are crucial for neuroprotection and cognitive function. This suggests potential benefits for neurodegenerative conditions and cognitive decline.
  3. Anti-Aggregation Properties: Semax has demonstrated the ability to prevent amyloid-beta aggregation, a key factor in Alzheimer's disease pathology. This anti-aggregating property highlights its potential as a therapeutic agent for neurodegenerative diseases.
  4. Emotional Stability: N-Acetyl Semax has shown potential in promoting emotional stability and reducing anxiety, making it a versatile tool for managing psychological well-being.
  5. Stroke Recovery: In a study involving 110 patients recovering from ischemic stroke, Semax administration was associated with increases in brain-derived neurotrophic factor (BDNF), which correlated with early rehabilitation.

  1. Comparative Studies: Further research is needed to assess the differences in bioavailability and efficacy between N-Acetyl Semax and Semax.
  2. Long-term Safety and Efficacy: Extended studies in human subjects are required to evaluate the long-term effects and safety profile of N-Acetyl Semax.
  3. Neurodegenerative Disorders: Exploration of its therapeutic applications in neurodegenerative disorders and cognitive decline is warranted, given its neuroprotective properties.
  4. Neuroplasticity and Synaptic Function: Investigation of N-Acetyl Semax's effects on neuroplasticity and synaptic function could provide insights into its mechanism of action.
  5. Metal Ion Interactions: Further research into N-Acetyl Semax's interactions with metal ions like copper and zinc could lead to potential applications in treating conditions associated with metal dyshomeostasis in the brain.

  1. I. P. Ashmarin et al., "A comparative analysis of the distribution of Semax and its C-terminal fragment Pro-Gly-Pro in organs and tissues of rats," Neuroscience and Behavioral Physiology, vol. 38, no. 9, pp. 929-935, 2008. [Online].
    Available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987924/
  2. Focal Point Vitality, "N Acetyl Semax: Improved Cognitive Function and Emotional Stability," 2023. [Online].
    Available: https://focalpointvitality.com/semax-peptide/
  3. O. V. Dolotov et al., "Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus," Brain Research, vol. 1117, no. 1, pp. 54-60, 2006. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/16962076/
  4. N. F. Myasoedov et al., "Semax, a peptide analog of ACTH(4-10) with cognitive effects, in stroke rehabilitation," Neuroscience Research Communications, vol. 25, no. 1, pp. 13-20, 1999. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/9195153/
  5. Walker, R.F., et al. (1994). "Growth hormone secretion in healthy elderly men: assessment by deconvolution analysis and approximate entropy algorithm." American Journal of Physiology, 267(1 Pt 1), E150-E157. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/8048505/
  6. T. P. Semenova et al., "The effect of semax on the temporary dynamics of brain-derived neurotrophic factor and nerve growth factor gene expression in the rat hippocampus and frontal cortex," Doklady Biological Sciences, vol. 391, pp. 304-307, 2003. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/15288367/
  7. A. Magrì et al., "Influence of the N-terminus acetylation of Semax, a synthetic analog of ACTH(4-10), on copper(II) and zinc(II) coordination and biological properties," Journal of Inorganic Biochemistry, vol. 164, pp. 59-69, 2016. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/27586814/
N-Acetyl Semax represents a promising avenue for cognitive enhancement and neuroprotection, with ongoing research likely to uncover further benefits and applications. As with all research peptides, it is important to use N-Acetyl Semax in controlled research settings, and its potential benefits and risks require further scientific scrutiny before any clinical applications can be considered.